Christopher A. Walsh Laboratory
Division of Genetics & Genomics
Developmental Disorders of the Brain
We study the genetics and molecular biology of the developing cerebral cortex, the brain’s largest structure, to advance understanding, diagnosis and management of human neurological diseases, including epilepsy, intellectual disability and autism. We are applying four interrelated perspectives in our approach: Evolution, Neurological Disorders, Cell Lineage and Aging, and Functional Analysis and Modeling.
Nature Aging and Azlforum
Check out these articles from Nature Aging and Alzforum! These articles discuss the work and study on “Somatic cancer variants enriched in Alzheimer’s
disease microglia-like cells drive inflammatory and proliferative states” (Cell) and “Somatic mosaicism in ALS and FTD identifies focal mutations associated with widespread degeneration” (Nature Genetics).
Other articles were posted by Precision Medicine and Nature – Research Briefing!
Educational Video
A Fourth-Year Medical Student at Texas Tech University Health Sciences Center took an interest in one of our lab’s article written by previous postdoc, Dr. Xuyu Qian, Spatial transcriptomics reveals human cortical layer and area specification.
From that article, they created an AI-assisted education YouTube video discussing the paper’s main findings. Check it out here!
Check out this article!
Check out this amazing feature on one of our previous graduate students, Maya Talukdar!
Why Is Autism More Common in Males?